Abstract
Before microbiological assay, cefamandole nafate should be hydrolyzed for 1 h at 37 degrees C in pH 8 buffer (0.1 M) or for 30 min at room temperature in aqueous solutions containing 1.25 molar equivalents of sodium carbonate.
Full text
PDF


Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Indelicato J. M., Wilham W. L., Cerimele B. J. Conversion of cefamandole nafate to cefamandole sodium. J Pharm Sci. 1976 Aug;65(8):1175–1178. doi: 10.1002/jps.2600650811. [DOI] [PubMed] [Google Scholar]
- Turner J. R., Preston D. A., Wold J. S. Delineation of the relative antibacterial activity of cefamandole and cefamandole nafate. Antimicrob Agents Chemother. 1977 Jul;12(1):67–72. doi: 10.1128/aac.12.1.67. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wold J. S., Joost R. R., Black H. R., Griffith R. S. Hydrolysis of cefamandole nafate to cefamandole in vivo. J Infect Dis. 1978 May;137 (Suppl):S17–S24. doi: 10.1093/infdis/137.supplement.s17. [DOI] [PubMed] [Google Scholar]
