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. 1979 Nov;16(5):680–682. doi: 10.1128/aac.16.5.680

Relative potencies of different anti-herpes agents in the topical treatment of cutaneous herpes simplex virus infection of athymic nude mice.

J Descamps, E De Clercq, P J Barr, A S Jones, R T Walker, P F Torrence, D Shugar
PMCID: PMC352929  PMID: 526011

Abstract

Thirteen established anti-herpes compounds have been directly compared in a single assay system for their effects on the development of herpetic skin lesions, and mortality associated therewith, in athymic nude (nu/nu) mice inoculated intracutaneously with herpes simplex virus type 1 (KOS). When applied topically (at 1% in a water-soluble ointment), phosphonoacetic acid, E-5-(2-bromovinyl)-2'-deoxyuridine, acycloguanosine, and trisodium phosphonoformate emerged as the most active agents.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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