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. 1979 Feb;29(2):501–506. doi: 10.1128/jvi.29.2.501-506.1979

Genes controlling receptors for ecotropic and xenotropic type C virus in Mus cervicolor and Mus musculus.

T H Marshall, U R Rapp
PMCID: PMC353182  PMID: 219245

Abstract

Gene loci controlling cell surface receptors for murine leukemia virus were studied by using murine X Chinese hamster hybrid cells. Hybrids which exclusively segregate murine chromosomes were made by fusing Mus cervicolor and Mus musculus lymphocytes to hamster fibroblasts. Sensitivity to Moloney murine leukemia virus infecotion and specific binding of the envelope glycoprotein of Rauscher murine leukemia virus (gp70) cosegregate and isozyme analysis show an association with chromosome 5 in both species. With the possible exception of one clone, no evidence was found for a proviral integration site independent of chromosome 5. Evidence is presented for additional unlinked ectropic and xenotropic receptors independent of chromosome 5.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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