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. 1979 Feb;29(2):794–798. doi: 10.1128/jvi.29.2.794-798.1979

Oligonucleotide mapping studies of standard and defective Sindbis virus RNA.

D Dohner, S Monroe, B Weiss, S Schlesinger
PMCID: PMC353214  PMID: 430611

Abstract

Oligonucleotide mapping studies of the RNA from standard and defective interfering particles of Sindbis virus demonstrate that 3'- and 5'-terminal regions of the genome are conserved in the defective RNAs. These studies also suggest that defective RNAs contain multiple deletions.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Brzeski H., Kennedy S. I. Synthesis of Sindbis virus nonstructural polypeptides in chicken embryo fibroblasts. J Virol. 1977 May;22(2):420–429. doi: 10.1128/jvi.22.2.420-429.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Cancedda R., Villa-Komaroff L., Lodish H. F., Schlesinger M. Initiation sites for translation of sindbis virus 42S and 26S messenger RNAs. Cell. 1975 Oct;6(2):215–222. doi: 10.1016/0092-8674(75)90012-4. [DOI] [PubMed] [Google Scholar]
  3. Clegg J. C., Brzeski H., Kennedy S. I. RNA polymerase components in Semliki Forest virus-infected cells: synthesis from large precursors. J Gen Virol. 1976 Sep;32(3):413–430. doi: 10.1099/0022-1317-32-3-413. [DOI] [PubMed] [Google Scholar]
  4. Clewley J. P., Kennedy S. I. Purification and polypeptide composition of Semliki Forest virus RNA polymerase. J Gen Virol. 1976 Sep;32(3):395–411. doi: 10.1099/0022-1317-32-3-395. [DOI] [PubMed] [Google Scholar]
  5. Coffin J. M., Billeter M. A. A physical map of the Rous sarcoma virus genome. J Mol Biol. 1976 Jan 25;100(3):293–318. doi: 10.1016/s0022-2836(76)80065-4. [DOI] [PubMed] [Google Scholar]
  6. Domingo E., Sabo D., Taniguchi T., Weissmann C. Nucleotide sequence heterogeneity of an RNA phage population. Cell. 1978 Apr;13(4):735–744. doi: 10.1016/0092-8674(78)90223-4. [DOI] [PubMed] [Google Scholar]
  7. Faller D. V., Hopkins N. T1 oligonucleotide maps of N-, B-, and B leads to NB-tropic murine leukemia viruses derived from BALB/c. J Virol. 1978 Apr;26(1):143–152. doi: 10.1128/jvi.26.1.143-152.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Flanegan J. B., Petterson R. F., Ambros V., Hewlett N. J., Baltimore D. Covalent linkage of a protein to a defined nucleotide sequence at the 5'-terminus of virion and replicative intermediate RNAs of poliovirus. Proc Natl Acad Sci U S A. 1977 Mar;74(3):961–965. doi: 10.1073/pnas.74.3.961. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Guild G. M., Flores L., Stollar V. Defective interfering particles of Sindbis virus. IV. Virion RNA species and molecular weight determination of defective double-stranded RNA. Virology. 1977 Mar;77(1):158–174. doi: 10.1016/0042-6822(77)90415-9. [DOI] [PubMed] [Google Scholar]
  10. Guild G. M., Stollar V. Defective interfering particles of Sindbis virus. V. Sequence relationships between SVSTD 42 S RNA and intracellular defective viral RNAs. Virology. 1977 Mar;77(1):175–188. doi: 10.1016/0042-6822(77)90416-0. [DOI] [PubMed] [Google Scholar]
  11. Huang A. S. Viral pathogenesis and molecular biology. Bacteriol Rev. 1977 Dec;41(4):811–821. doi: 10.1128/br.41.4.811-821.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Johnston R. E., Tovell D. R., Brown D. T., Faulkner P. Interfering passages of Sindbis virus: concomitant appearance of interference, morphological variants, and trucated viral RNA. J Virol. 1975 Oct;16(4):951–958. doi: 10.1128/jvi.16.4.951-958.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Kennedy S. I., Bruton C. J., Weiss B., Schlesinger S. Defective interfering passages of Sindbis virus: nature of the defective virion RNA. J Virol. 1976 Sep;19(3):1034–1043. doi: 10.1128/jvi.19.3.1034-1043.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Kennedy S. I. Sequence relationships between the genome and the intracellular RNA species of standard and defective-interfering Semliki Forest virus. J Mol Biol. 1976 Dec;108(2):491–511. doi: 10.1016/s0022-2836(76)80132-5. [DOI] [PubMed] [Google Scholar]
  15. Leppert M., Kort L., Kolakofsky D. Further characterization of Sendai virus DI-RNAs: a model for their generation. Cell. 1977 Oct;12(2):539–552. doi: 10.1016/0092-8674(77)90130-1. [DOI] [PubMed] [Google Scholar]
  16. Wengler G., Wengler G. Localization of the 26-S RNA sequence on the viral genome type 42-S RNA isolated from SFV-infected cells. Virology. 1976 Aug;73(1):190–199. doi: 10.1016/0042-6822(76)90073-8. [DOI] [PubMed] [Google Scholar]

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