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. 1979 Apr;30(1):394–396. doi: 10.1128/jvi.30.1.394-396.1979

Simian Virus 40 t Antigen Affects the Sensitivity of Cellular DNA Synthesis to Theophylline

Kathleen Rundell 1, Janet Cox 1
PMCID: PMC353334  PMID: 225524

Abstract

Cellular DNA synthesis induced by simian virus 40 mutants that lack t antigen is sensitive to concentrations of theophylline that do not affect wild-type-induced synthesis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bouck N., Beales N., Shenk T., Berg P., di Mayorca G. New region of the simian virus 40 genome required for efficient viral transformation. Proc Natl Acad Sci U S A. 1978 May;75(5):2473–2477. doi: 10.1073/pnas.75.5.2473. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Crawford L. V., Cole C. N., Smith A. E., Paucha E., Tegtmeyer P., Rundell K., Berg P. Organization and expression of early genes of simian virus 40. Proc Natl Acad Sci U S A. 1978 Jan;75(1):117–121. doi: 10.1073/pnas.75.1.117. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Froehlich J. E., Rachmeler M. Inhibition of cell growth in the G1 phase by adenosine 3', 5'-cyclic monophosphate. J Cell Biol. 1974 Jan;60(1):249–257. doi: 10.1083/jcb.60.1.249. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Hirt B. Selective extraction of polyoma DNA from infected mouse cell cultures. J Mol Biol. 1967 Jun 14;26(2):365–369. doi: 10.1016/0022-2836(67)90307-5. [DOI] [PubMed] [Google Scholar]
  5. Postel E. H., Levine A. J. The requirement of simian virus 40 gene A product for the stimulation of cellular thymidine kinase activity after viral infection. Virology. 1976 Aug;73(1):206–215. doi: 10.1016/0042-6822(76)90075-1. [DOI] [PubMed] [Google Scholar]
  6. Schlegel R., Benjamin T. L. Cellular alterations dependent upon the polyoma virus Hr-t function: separation of mitogenic from transforming capacities. Cell. 1978 Jul;14(3):587–599. doi: 10.1016/0092-8674(78)90244-1. [DOI] [PubMed] [Google Scholar]
  7. Shenk T. E., Carbon J., Berg P. Construction and analysis of viable deletion mutants of simian virus 40. J Virol. 1976 May;18(2):664–671. doi: 10.1128/jvi.18.2.664-671.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Sleigh M. J., Topp W. C., Hanich R., Sambrook J. F. Mutants of SV40 with an altered small t protein are reduced in their ability to transform cells. Cell. 1978 May;14(1):79–88. doi: 10.1016/0092-8674(78)90303-3. [DOI] [PubMed] [Google Scholar]
  9. Tegtmeyer P. Altered patterns of protein synthesis in infection by SV40 mutants. Cold Spring Harb Symp Quant Biol. 1975;39(Pt 1):9–15. doi: 10.1101/sqb.1974.039.01.004. [DOI] [PubMed] [Google Scholar]

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