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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Pain. 2013 Jan;154(1):59–70. doi: 10.1016/j.pain.2012.09.002

Figure 1.

Figure 1

Differentially expressed miRNAs in the spinal (L6-S1) dorsal horns following neonatal zymosan-induced cystitis. A: miRNAs that demonstrate up-regulation and down-regulation using two different zymosan treatment protocols. The data was analyzed using GeneSpring v11 software and unpaired Mann-whiney Test to identify differentially expressed miRNAs (n=3/group, p<0.05 vs saline controls). B: differentially expressed miRNAs with 3′UTR binding sites for various genes associated with spinal GABAergic system. C: schematic representation of 3′UTR of GABAAα−1 gene demonstrating multiple complementary binding sites of miR-181a and miR-181b.