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. 1980 Oct;36(1):291–294. doi: 10.1128/jvi.36.1.291-294.1980

Possible cell surface receptor for Friend murine leukemia virus isolated with viral envelope glycoprotein complexes.

P J Robinson, G Hunsmann, J Schneider, V Schirrmacher
PMCID: PMC353640  PMID: 7441823

Abstract

Water-soluble multimeric complexes of Friend leukemia virus envelope glycoprotein gp85 bind specifically to C57BL/6 mouse spleen leukocytes. Such complexes were used to isolate cell surface receptors for the virus, using an immunoprecipitation technique. The putative rceptor has a molecular weight of 14,000. Mouse H-2 histocompatibility antigens, which are receptors for Semliki Forest virus, are not receptors for Friend leukemia virus.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bishayee S., Strand M., August J. T. Cellular membrane receptors for oncovirus envelope glycoprotein: properties of the binding reaction and influence of different reagents on the substrate and the receptors. Arch Biochem Biophys. 1978 Jul;189(1):161–171. doi: 10.1016/0003-9861(78)90129-7. [DOI] [PubMed] [Google Scholar]
  2. Blank K. J., Lilly F. Evidence for an H-2/viral protein complex on the cell surface as the basis for the H-2 restriction of cytotoxicity. Nature. 1977 Oct 27;269(5631):808–809. doi: 10.1038/269808a0. [DOI] [PubMed] [Google Scholar]
  3. Bubbers J. E., Chen S., Lilly F. Nonrandom inclusion of H-2K and H-2D antigens in Friend virus particles from mice of various strains. J Exp Med. 1978 Feb 1;147(2):340–351. doi: 10.1084/jem.147.2.340. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. DeLarco J., Todaro G. J. Membrane receptors for murine leukemia viruses: characterization using the purified viral envelope glycoprotein, gp71. Cell. 1976 Jul;8(3):365–371. doi: 10.1016/0092-8674(76)90148-3. [DOI] [PubMed] [Google Scholar]
  5. Fowler A. K., Twardzik D. R., Reed C. D., Weislow O. S., Hellman A. Binding characteristics of Rauscher leukemia virus envelope glycoprotein gp71 to murine lymphoid cells. J Virol. 1977 Dec;24(3):729–735. doi: 10.1128/jvi.24.3.729-735.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Helenius A., Morein B., Fries E., Simons K., Robinson P., Schirrmacher V., Terhorst C., Strominger J. L. Human (HLA-A and HLA-B) and murine (H-2K and H-2D) histocompatibility antigens are cell surface receptors for Semliki Forest virus. Proc Natl Acad Sci U S A. 1978 Aug;75(8):3846–3850. doi: 10.1073/pnas.75.8.3846. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Helenius A., von Bonsdorff C. H. Semlike Forest virus membrane proteins. Preparation and characterization of spike complexes soluble in detergent-free medium. Biochim Biophys Acta. 1976 Jul 15;436(4):895–899. doi: 10.1016/0005-2736(76)90421-1. [DOI] [PubMed] [Google Scholar]
  8. Kvist S., Ostberg L., Persson H., Philipson L., Peterson P. A. Molecular association between transplantation antigens and cell surface antigen in adenovirus-transformed cell line. Proc Natl Acad Sci U S A. 1978 Nov;75(11):5674–5678. doi: 10.1073/pnas.75.11.5674. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Laemmli U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 1970 Aug 15;227(5259):680–685. doi: 10.1038/227680a0. [DOI] [PubMed] [Google Scholar]
  10. Lemke H., Hämmerling G. J., Hämmerling U. Fine specificity analysis with monoclonal antibodies of antigens controlled by the major histocompatibility complex and by the Qa/TL region in mice. Immunol Rev. 1979;47:175–206. doi: 10.1111/j.1600-065x.1979.tb00293.x. [DOI] [PubMed] [Google Scholar]
  11. Lerner R. A., Wilson C. B., Villano B. C., McConahey P. J., Dixon F. J. Endogenous oncornaviral gene expression in adult and fetal mice: quantitative, histologic, and physiologic studies of the major viral glycorprotein, gp70. J Exp Med. 1976 Jan 1;143(1):151–166. doi: 10.1084/jem.143.1.151. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Oie H. K., Gazdar A. F., Lalley P. A., Russell E. K., Minna J. D., DeLarco J., Todaro G. J., Francke U. Mouse chromosome 5 codes for ecotropic murine leukaemia virus cell-surface receptor. Nature. 1978 Jul 6;274(5666):60–62. doi: 10.1038/274060a0. [DOI] [PubMed] [Google Scholar]
  13. Schneider J., Falk H., Hunsmann G. Envelope polypeptides of Friend leukemia virus: purification and structural analysis. J Virol. 1980 Feb;33(2):597–605. doi: 10.1128/jvi.33.2.597-605.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Schneider J., Hunsmann G. Surface expression of murine leukemia virus structural polypeptides on host cells and the virion. Int J Cancer. 1978 Aug 15;22(2):204–213. doi: 10.1002/ijc.2910220215. [DOI] [PubMed] [Google Scholar]
  15. Schneider J., Schwarz H., Hunsmann G. Rosettes from Friend leukemia virus envelope: preparation and physicochemical and partial biological characterization. J Virol. 1979 Feb;29(2):624–632. doi: 10.1128/jvi.29.2.624-632.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Schrader J. W., Cunningham B. A., Edelman G. M. Functional interactions of viral and histocompatibility antigens at tumor cell surfaces. Proc Natl Acad Sci U S A. 1975 Dec;72(12):5066–5070. doi: 10.1073/pnas.72.12.5066. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Trowbridge I. S., Ralph P., Bevan M. J. Differences in the surface proteins of mouse B and T cells. Proc Natl Acad Sci U S A. 1975 Jan;72(1):157–161. doi: 10.1073/pnas.72.1.157. [DOI] [PMC free article] [PubMed] [Google Scholar]

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