Table 2.
Hazard ratios and 95% CIs for 10 year risk of cardiovascular events in 782 adults from the CHS who had diabetes
| Final model | Basic model | +Biomarkers | +Subclinical measures |
|---|---|---|---|
|
|
|||
| Age (years) | 1.05 (1.03, 1.08) | 1.06 (1.03, 1.08) | 1.03 (1.01, 1.06) |
| Former smoker | 1.29 (0.98, 1.70) | 1.25 (0.95, 1.64) | 1.10 (0.83, 1.46) |
| Current smoker | 1.64 (1.08, 2.50) | 1.52 (0.99, 2.32) | 1.19 (0.77, 1.84) |
| Systolic BP per 10 mmHg up to 160 | 1.15 (1.07, 1.24) | 1.15 (1.07, 1.24) | 1.11 (1.03, 1.20) |
| Total cholesterol per mmol/l | 1.17 (1.05, 1.31) | 1.18 (1.05, 1.33) | 1.16 (1.03, 1.31) |
| HDL-cholesterol per mmol/l | 0.79 (0.53, 1.18) | 0.82 (0.54, 1.23) | 0.86 (0.56, 1.30) |
| Creatinine >110.5 μmol/l | 1.43 (1.05, 1.96) | 1.36 (1.00, 1.86) | 1.31 (0.96, 1.78) |
| Oral hypoglycaemic agent or insulin use | 1.71 (1.33, 2.19) | 1.73 (1.35, 2.22) | 1.57 (1.21, 2.03) |
| CRP per 10 nmol/l up to 190 nmol/l | 1.03 (1.01, 1.06) | 1.03 (1.00, 1.05) | |
| ABI <1 | 1.52 (1.16, 1.99) | ||
| ECG left ventricular hypertrophy | 1.78 (1.08, 2.95) | ||
| Internal carotid IMT per mm up to 3 | 1.66 (1.35, 2.04) | ||
| Summary measures | |||
| Akaike’s information criterion | 2934 | 2930 | 2898 |
| Bayes’ information criterion | 2971 | 2972 | 2954 |
| Harrell’s C statistic | 0.64 | 0.64 | 0.68 |
| Hosmer–Lemeshow p value | 0.25 | 0.87 | 0.65 |
CRP, C-reactive protein