Table 6.
Frequency Distributions of BRAF Genotypes by Age in Patients with Papillary Thyroid Cancer
| Variants | <45 years, n (%) | ≥45 years, n (%) | OR [CI]a |
|---|---|---|---|
| rs1042179: A>G | |||
| AA | 132 (71.4) | 127 (69.8) | 1.00 |
| AG | 48 (25.9) | 50 (27.5) | 1.49 [0.68–1.75] |
| GG | 5 (2.7) | 5 (2.7) | 0.87 [0.24–3.20] |
| rs11762469: A>T | |||
| AA | 121 (65.1) | 127 (69.8) | 1.00 |
| AT | 61 (32.8) | 50 (27.5) | 0.84 [0.51–1.27] |
| TT | 4 (2.2) | 5 (3.6) | 1.21 [0.31–4.64] |
| rs17161747: G>C | |||
| GG | 128 (68.8) | 116 (63.7) | 1.00 |
| GC | 50 (26.9) | 61 (33.5) | 1.34 [0.84–2.12] |
| CC | 8 (4.3) | 5 (2.7) | 0.65 [0.20–2.10] |
| rs3748093: T>A | |||
| TT | 104 (55.9) | 115 (63.5) | 1.00 |
| AT | 76 (40.9) | 52 (28.7) | 0.64 [0.41–0.99]b |
| AA | 6 (3.2) | 14 (7.7) | 2.05 [0.75–5.59] |
a
ORs are adjusted for sex, cancer familial history, drinking alcohol, and smoking.
b
Boldface indicates statistical significance (p<0.05).