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. 1978 May;26(2):236–242. doi: 10.1128/jvi.26.2.236-242.1978

RNA of mouse hepatitis virus.

M M Lai, S A Stohlman
PMCID: PMC354060  PMID: 207885

Abstract

The RNA of mouse hepatitis virus, a coronavirus, was isolated from the virus released early in the infection and analyzed by sucrose gradient sedimentation and electrophoresis. It was found to consist of a piece of single-stranded RNA of about 60S. Its molecular weight was estimated to be 5.4 X 10(6) by electrophoresis in methylmercury-agarose gels. At least one third of the RNA contained polyadenylated sequences. It is, therefore, probably positive stranded. The virus harvested late in the infection contained, in addition to 60S, some 30 to 50S RNA that are possibly degradation products of the 60S RNA. No difference in the electrophoretic behavior could be detected between the RNA isolated from a pathogenic (JHM) and a nonpathogenic (A59) strain.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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