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. 1975 Feb;15(2):338–347. doi: 10.1128/jvi.15.2.338-347.1975

RNA polymerase associated with virions of pike fry rhabdovirus.

P Roy, H F Clark, H P Madore, D H Bishop
PMCID: PMC354458  PMID: 1167603

Abstract

The association of an RNA-dependent RNA polymerase activity with virions of pike fry rhabdovirus has been demonstrated by both in vitro and in vivo studies. The temperature optimum for the in vitro assay is around 20 C, although enzyme activity can be observed at 4 C. Preparations of pike fry virus possess a glycoprotein, a membrane protein, a nucleoprotein, an L protein, and a phosphoprotein, as well as an RNA of about 3.8 times 10-6 mol wt. A protein kinase activity has been found associated with virus preparations. In vitro RNA product analyses indicate that the virus-associated enzyme functions principally as a transcriptase synthesizing viral-complementary, heteropolymeric RNA.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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