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. 1975 Apr;15(4):806–811. doi: 10.1128/jvi.15.4.806-811.1975

Differential accumulation of virus-specific RNA during the cell cycle of adenovirus-transformed rat embyro cells.

P R Hoffmann, J E Darnell Jr
PMCID: PMC354523  PMID: 1167915

Abstract

In adenovirus type 2-transformed rat embryo cells there is a threefold greater incorporation of [3-H]uridine into virus-specific RNA early in S phase than in late S or G2. This heightened accumulation of labeled RNA is true for both nuclear and cytoplasmic virus-specific labeling. Inhibition of DNA synthesis decreases the virus-specific RNA labeling, whereas reversal of inhibition again allows the elevated level of virus-specific RNA labeling.

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Selected References

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