Table 4.
Average number of antihypertensive agents and number of drug changes per patient, and drug costs per antihypertensive agent over six months
| Mean (SD)
|
P-value | ||
|---|---|---|---|
| Control | Intervention | ||
| Number of dose-specified antihypertensive agents | 3.09 (1.82) | 4.14 (2.25) | <0.001 |
| Number of drug changesf | 1.18 (1.58) | 3.24 (2.43) | <0.001 |
| Unadjusted drug costs per dose-specified antihypertensive agent | $109.24 (116.15) | $90.95 (65.69) | 0.03 |
| Total adjustedg drug costs | $287.64 (171.45) | $383.53 (171.45) | <0.001 |
| Adjusted drug costsg per dose-specified antihypertensive agent | $104.92 (25.89) | $95.99 (25.89) | 0.32 |
f
Drug changes included starting new drugs, increasing doses, decreasing doses, and discontinuing drugs.
g
Adjusted costs were the results from multiple regression analysis controlling for age, gender, race, marital status, smoking status, alcohol intake, number of medications at baseline, number of comorbidities at baseline, systolic blood pressure at baseline, and diastolic blood pressure at baseline.