Table 1.

Adiponectin and combined vascular events (Hazard Ratio, 95% Confidence Interval), N=692 events (overall N=2900)

Adiponectin	Model 1	Model 2	Model 3	Model 4	Model 5
Continuous	1.04 (1.03–1.05)	1.00 (0.99–1.02)	1.03 (1.01–1.04)	1.03 (1.01–1.05)	1.02 (1.01–1.03)
Quartile 1	0.63 (0.51–0.77)	1.05 (0.84–1.31)	0.73 (0.57–0.94)	0.64 (0.47–0.87)	0.83 (0.67–1.03)
Quartile 2	0.50 (0.41–0.62)	0.82 (0.65–1.03)	0.61 (0.47–0.79)	0.49 (0.44–0.80)	0.69 (0.54–0.87)
Quartile 3	0.66 (0.54–0.81)	0.88 (0.71–1.07)	0.73 (0.58–0.91)	0.75 (0.58–0.98)	0.75 (0.60–0.93)
Quartile 4	ref	ref	ref	ref	ref

Model 1: Univariate

Model 2: Adjusting for age, sex, race/ethnicity

Model 3: Adjusting for age, sex, race/ethnicity, smoking, hypertension, diabetes, low density lipoprotein cholesterol, high density lipoprotein cholesterol, triglycerides, waist circumference, moderate alcohol use, moderate-heavy physical activity, previous cardiac disease history

Model 4: Adjusting for the variables in model 3 + hsCRP (N=2091)

Model 5: Adjusting for the NOMAS global vascular risk score