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. 1975 Oct;16(4):959–973. doi: 10.1128/jvi.16.4.959-973.1975

Physical map of the BK virus genome.

P M Howley, G Khoury, J C Byrne, K K Takemoto, M A Martin
PMCID: PMC354758  PMID: 170425

Abstract

Two new human papovavirus isolates (JMV and MMV) from the urines of patients with Wiskott-Aldrich syndrome were morphologically and serologically identical to BK virus (BKV). The genomes of these two new isolates were found to be indistinguishable from prototype BKV DNA in a variety of nucleic acid hybridization experiments. Like BKV DNA, JMV and MMV DNAs share approximately 20% of their polynucleotide sequences with simian virus 40 DNA. The genome of JMV was indistinguishable from that of BKV by restriction endonuclease analysis; MMV DNA contained three instead of four R-Hind cleavage sites and one rather than no R-HpaII cleavage sites. Physical maps of the BKV and MMV genomes were constructed using restriction endonucleases, and these maps were oriented to the map of simian virus 40 DNA.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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