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. 1976 Jun;18(3):950–955. doi: 10.1128/jvi.18.3.950-955.1976

Prophage induction and inactivation by UV light.

B J Barnhart, S H Cox, J H Jett
PMCID: PMC354795  PMID: 1083915

Abstract

Analysis of the induction curves for UV light-irradiated Haemophilus influenzae lysogens and the distribution of pyrimidine dimers in a repair-deficient lysogen suggests that one dimer per prophage-size segment of the host bacterial chromosome is necessary as a preinduction event. The close correlations obtained prompted a renewed consideration of the possibility that direct prophage induction occurs when one dimer is stabilized within the prophage genome. The host excision-repair system apparently functions to reduce the probability of "stabilizing" within the prophage those dimers that are necessary for induction and inactivation. The presence of the inducible defective prophage in strain Rd depresses the inducibility of prophage HP1c1.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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