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. 2013 Jan 3;154(2):738–748. doi: 10.1210/en.2012-1790

Figure 5.

Figure 5.

Reduced expression of PIT1 protein in Lhx3W227ter/W227ter animals on C57BL/6 and 129/Sv backgrounds. PIT1 protein was detected using IHC in pituitary sections of Lhx3W227ter/W227ter homozygote and WT mice at E17.5 on a 98.4% C57BL/6 or 129/Sv background. Decreased expression was seen in Lhx3W227ter/W227ter animals on a C57BL/6 background, and no expression was seen in Lhx3W227ter/W227ter mice on a 129/Sv background. An example of a hypoplastic, bifurcated AP lobe is labeled (asterisk).