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. 1976 Jul;19(1):267–270. doi: 10.1128/jvi.19.1.267-270.1976

Characteristics of the genome of human infantile enteritis virus (Rotavirus).

R D Schnagl, I H Holmes
PMCID: PMC354854  PMID: 820876

Abstract

Thermal denaturation studies and polyacrylamide gel electrophoretic analysis have shown that the genome of human infantile enteritis virus (human rotavirus) consists of approximately 11 double-stranded segments. Differences in the molecular weights of some of the corresponding genome segments are apparent between different isolates of the virus.

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Selected References

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  1. Bishop R. F., Davidson G. P., Holmes I. H., Ruck B. J. Virus particles in epithelial cells of duodenal mucosa from children with acute non-bacterial gastroenteritis. Lancet. 1973 Dec 8;2(7841):1281–1283. doi: 10.1016/s0140-6736(73)92867-5. [DOI] [PubMed] [Google Scholar]
  2. Flewett T. H., Bryden A. S., Davies H. Letter: Virus particles in gastroenteritis. Lancet. 1973 Dec 29;2(7844):1497–1497. doi: 10.1016/s0140-6736(73)92760-8. [DOI] [PubMed] [Google Scholar]
  3. Flewett T. H., Bryden A. S., Davies H., Woode G. N., Bridger J. C., Derrick J. M. Relation between viruses from acute gastroenteritis of children and newborn calves. Lancet. 1974 Jul 13;2(7872):61–63. doi: 10.1016/s0140-6736(74)91631-6. [DOI] [PubMed] [Google Scholar]
  4. Infantile enteritis viruses: morphogenesis and morphology. J Virol. 1975 Oct;16(4):937–943. doi: 10.1128/jvi.16.4.937-943.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Kapikian A. Z., Cline W. L., Mebus C. A., Wyatt R. G., Kalica A. R., James H. D., Jr, VanKirk D., Chanock R. M. New complement-fixation test for the human reovirus-like agent of infantile gastroenteritis. Nebraska calf diarrhea virus used as antigen. Lancet. 1975 May 10;1(7915):1056–1061. doi: 10.1016/s0140-6736(75)91827-9. [DOI] [PubMed] [Google Scholar]
  6. Kapikian A. Z., Kim H. W., Wyatt R. G., Rodriguez W. J., Ross S., Cline W. L., Parrott R. H., Chanock R. M. Reoviruslike agent in stools: association with infantile diarrhea and development of serologic tests. Science. 1974 Sep 20;185(4156):1049–1053. doi: 10.1126/science.185.4156.1049. [DOI] [PubMed] [Google Scholar]
  7. Loening U. E. The determination of the molecular weight of ribonucleic acid by polyacrylamide-gel electrophresis. The effects of changes in conformation. Biochem J. 1969 Jun;113(1):131–138. doi: 10.1042/bj1130131. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Middleton P. J., Petric M., Szymanski M. T. Propagation of infantile gastroenteritis virus (orbi-group) in conventional and germfree piglets. Infect Immun. 1975 Dec;12(6):1276–1280. doi: 10.1128/iai.12.6.1276-1280.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Newman J. F., Brown F., Bridger J. C., Woode G. N. Characterisation of a rotavirus.20b. Nature. 1975 Dec 18;258(5536):631–633. doi: 10.1038/258631a0. [DOI] [PubMed] [Google Scholar]
  10. Oliver D., Chalkley R. An improved photographic system for polyacrylamide gels. Anal Biochem. 1971 Dec;44(2):540–542. doi: 10.1016/0003-2697(71)90242-9. [DOI] [PubMed] [Google Scholar]
  11. Rodger S. M., Schnagl R. D., Holmes I. H. Biochemical and biophysical characteristics of diarrhea viruses of human and calf origin. J Virol. 1975 Nov;16(5):1229–1235. doi: 10.1128/jvi.16.5.1229-1235.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Schnagl R. D., Holmes I. H. Polyacrylamide gel electrophoresis of the genomes of two orbiviruses: D'Aguilar and Eubenangee. Intervirology. 1975;5(5):300–304. doi: 10.1159/000149926. [DOI] [PubMed] [Google Scholar]
  13. Shatkin A. J., Sipe J. D., Loh P. Separation of ten reovirus genome segments by polyacrylamide gel electrophoresis. J Virol. 1968 Oct;2(10):986–991. doi: 10.1128/jvi.2.10.986-991.1968. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Verwoerd D. W., Els H. J., De Villiers E. M., Huismans H. Structure of the bluetongue virus capsid. J Virol. 1972 Oct;10(4):783–794. doi: 10.1128/jvi.10.4.783-794.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Verwoerd D. W., Louw H., Oellermann R. A. Characterization of bluetongue virus ribonucleic acid. J Virol. 1970 Jan;5(1):1–7. doi: 10.1128/jvi.5.1.1-7.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]

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