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. 1976 Aug;19(2):318–324. doi: 10.1128/jvi.19.2.318-324.1976

Action of ethyl and methyl methane sulfonates on DNA injection and genetic recombination in T7 bacteriophage.

B Karska-Wysocki, M D Mamet-Bratley, W G Verly
PMCID: PMC354868  PMID: 183007

Abstract

After treatment with methyl or ethyl methane sulfonate, T7 amber mutants display a reduced capacity for recombination. Moreover, alkylation reduces recombination frequency involving markers on the right-hand side of the genetic map more than it reduces recombination frequency involving markers on the left-hand side. We interpret this to mean that alkylation can stop DNA injection at any point along the DNA molecule, and that T7 phage injects its DNA in a unique fashion starting from the end carrying the genes for early proteins.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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