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. 2006 Sep;2(3):126–135. doi: 10.1007/BF03161027

Phthalates in food and medical devices

Karen Chou 1,3,✉, Robert O Wright 2,3
PMCID: PMC3550149  PMID: 18077888

Summary

Phthalates are ubiquitous environmental chemicals with a broad range of potential adverse health effects. Exposure pathways include air, water, packaged food and household products. Biological effects include disruption of the balance of sex hormones, allergic reactions, and enzyme inhibition. Carcinogenicity is seen in animals. In human studies, phthalates have been associated with poorer sperm quality, the symptomatology of asthma, and shortened AGD. Given the widespread use of phthalates in industrialized countries, further research, particularly on birth outcomes, endocrine disruption and child development are greatly needed.

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Abbreviations

BBP

Butyl benzyl phthalate

BiBP

Butyl isobutyl phthalate

BBzP

Butyl benzyl phthalate

BW

Body Weight

DBP

Dibutyl phthalate

DEHP

Di (2-ethylhexyl) phthalate

DEP

Diethyl phthalate

DiDP

Di(isodecyl) phthalate

DINP

Diisononyl phthalate

DIOP

Diisooctyl phthalate

DiBP

Di(isobutyl) phthalate

DMP

Dimethyl-phthalate

DnNP

Di-n-nonyl phthalate

DnOP

Di-n-octyl phthalate

ECMO

Extracorporeal membrane oxygenation

GIT

Gastro-intestinal tract

IT

Tolerable intake

MBP

Mono-n-butyl phthalate

MBzP

Monobenzyl phthalate

MCL

Maximum Contaminant Level

MCPP

Mono-3-carboxypropyl phthalate

MEHP

Monoethylhexyl phthalate

MEP

Monoethyl phthalate

MEHHP

Mono-2-ethyl-5-hydroxyhexyl phthalate

MEOHP

Mono-2-ethyl-5-oxohexyl phthalate

MiBP

Monoisobutyl phthalate

MMP

Monomethyl phthalate

TPN

Total parenteral nutrition

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