Abstract
Introduction
We report a large number of cases of pulmonary toxicity from 6 regional poison control centers associated with the use of a waterproofing-grout sealer. The identification of this illness occurred by means of the poison control center (PCC) national automated toxicosurveillance.
Materials and Methods
This is a retrospective case review of all cases of pulmonary toxicity following exposure to a waterproofing grout sealer from 6 regional PCCs including Michigan, Kentucky, Utah, Maine, Arizona, and Nebraska. The study period extended from June 1, 2005 to December 1, 2005.
Results
The vast majority of patients used the product at home (80%). Over half the patients presented within 3 hours of exposure. The most common presenting symptoms were shortness of breath (63%), cough (60%), and chest pain (44%). Wheezing (33%) and rales (23%) were the most common signs of clinical toxicity. One patient required endotracheal intubation. Thirty-seven percent of patients had signs of acute pneumonitis on initial chest x-ray. The mean presenting oxygen saturation was 89.5%. The most common treatment measures used were supplemental oxygen, bronchodilator therapy, oral steroids, and antibiotics. Over half of the study group required hospital admission.
Conclusion
The majority of patients in this study were adults using the product at home. Over one-third of patients had an abnormal x-ray upon presentation. Over half of the study group required hospital admission following exposure to this product. Medical professionals should be aware of the potential for pulmonary toxicity due to waterproofing aerosols.
Keywords: pneumonitis, Stand’n Seal Grout Sealer, fluoropolymer, waterproofing aerosol, toxicity
Full Text
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Footnotes
This research was presented in abstract form at the 2006 NACCT meeting: Daubert GP, Spiller H, Smolinske S. Pulmonary Toxicity Following Exposure to Waterproofing Grout Sealer.Clin Toxicol. 2006;44:608.
There was no outside funding of any kind used for this study.
References
- 1.Environmental Protection Agency [webpage on the Internet]. The Plain English Guide to the Clean Air Act. EPA-400-K-93-001. April 1993. Available from: http://www.thecre.com/fedlaw/legal14air/pegcaain.htm
- 2.Groot R. Sudden increase of acute respiratory illness using a spray product to waterproof clothing and shoes. J Toxicol Clin Toxicol. 2003;42:443–443. [Google Scholar]
- 3.Heinzer R, Ribordy V, Kuzoe B, et al. Recurrence of acute respiratory failure following use of waterproofing sprays. Thorax. 2004;59:541–542. [PMC free article] [PubMed] [Google Scholar]
- 4.Ishizawa J, Tujikama A, Kuroki Y, et al. Acute poisoning of a waterproofing spray. Nihon-Ili-Shinpou (Jpn) 1994;3638:47–50. [Google Scholar]
- 5.Kelly K, Ruffing R. Acute eosinophilic pneumonia following intentional inhalation of Scotchguard®. Ann Allergy. 1993;71:358–361. [PubMed] [Google Scholar]
- 6.Laliberté M, Sanfacone G, Blais R, et al. Acute pulmonary toxicity linked to use of a leather protector. Ann Emerg Med. 1995;25:841–844. doi: 10.1016/S0196-0644(95)70217-2. [DOI] [PubMed] [Google Scholar]
- 7.Lazor-Blanchet C, Rusca S, Vernez D, et al. Acute pulmonary toxicity following occupational exposure to a floor stain protector in the building industry in Switzerland. Int Arch Occup Environ Health. 2004;77:244–248. doi: 10.1007/s00420-004-0505-6. [DOI] [PubMed] [Google Scholar]
- 8.Perrone H, Passero M. Hydrocarbon aerosol pneumonitis in an adult. Arch Intern Med. 1983;143:1607–1608. doi: 10.1001/archinte.143.8.1607. [DOI] [PubMed] [Google Scholar]
- 9.CPSC. Tile Perfect, Inc. Announce Recall of Stand’n Seal™ Grout Sealer Due to Respiratory Problems. U.S. Consumer Product. August 31, 2005. 2005;Release #05-253.
- 10.Centers of Disease Control Acute respiratory illness linked to the use of aerosol leather conditioner—Oregon, December 1992. MMWR Morb Mortal Wkly Rep. 1993;41:965–967. [PubMed] [Google Scholar]
- 11.Centers of Disease Control Severe Acute Respiratory Illness Linked to Use of Shoe Sprays—Colorado, November 1993. MMWR Morb Mortal Wkly Rep. 1993;42:885–887. [PubMed] [Google Scholar]
- 12.Burkhart KK, Brett A, Petrini G, et al. Pulmonary toxicity following exposure to an aerosolized leather protector. J Toxicol Clin Toxicol. 1996;34:21–24. doi: 10.3109/15563659609020228. [DOI] [PubMed] [Google Scholar]
- 13.Yamashita M, Tanaka J, Hirai H, et al. Pulmonary collapse and pneumonia due to inhalation of water-proofing aerosols in female CD-1 mice. J Toxicol Clin Toxicol. 1995;33:631–637. doi: 10.3109/15563659509010620. [DOI] [PubMed] [Google Scholar]