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. 2009 Sep;5(3):151–157. doi: 10.1007/BF03161228

Case files of the medical toxicology fellowship at the New York City Poison Control: Bromism: Forgotten, but not gone

Daniel M Lugassy 1,✉, Lewis S Nelson 1
PMCID: PMC3550397  PMID: 19655290

Conclusion

After an extensive literature review, this appears to be the first case documenting bromide toxicity in a patient exposed to the product called Cordial de Monell, which contains potassium bromide. We have identified this product on store shelves in areas of New York City. We believe this child suffered from excess therapeutic sedative exposure due to her size, age, and repeated exposure. Bromism is not nearly as common as it once was, but several forms of bromide are still readily available. This diagnosis should be included in the differential diagnosis of patients who present with sedative-hypnotic-type intoxication. Elevations in the reported serum chloride levels and a negative anion gap are helpful findings if present, but our case and others before confirm that the lack of these features do not rule out this poisoning. This case further illustrates the need for clinicians to be diligent in obtaining thorough medication, dietary, herbal supplement, social, occupational, and cultural histories from their patients. Aggressive hydration with chloride-containing solutions is the cornerstone of treatment, and in severe cases dialysis may be considered. Bromides are not gone, and bromism should not be forgotten.

Keywords: bromism, bromides, negative anion gap, bromoderma

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