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Journal of Medical Toxicology logoLink to Journal of Medical Toxicology
. 2009 Dec;5(4):214–217. doi: 10.1007/BF03178270

Zigadenus poisoning treated with atropine and dopamine

Patrick West 1,, B Zane Horowitz 1
PMCID: PMC3550413  PMID: 19876855

Abstract

Introduction

Zigadenus (commonly known as “death camas” or “mountain camas”) is a common plant in the lilly family found throughout the United States. Its onion-like roots can be mistaken for an edible plant. Ingestion may cause hemodynamic instability which has successfully been treated with atropine. It has been suggested that vasopressors may be an effective therapy for this ingestion. We report the successful use of dopamine as therapy inZigadenus ingestion.

Case Report

A 45 year-old, previously healthy male presented to the ED with complaints of severe nausea and vomiting after ingesting two “wild onion” bulbs. He was noted to have marked hypotension and bradycardia in the ED, which initially responded to treatment with IV fluids and atropine. The plant was identified as a species ofZigadenus. After a second drop in heart rate and blood pressure in the ICU, hypotension and bradycardia were treated successfully with a dopamine infusion.

Discussion

Zigadenus ingestion presents with vomiting, hypotension and bradycardia. The hemodynamic instability responded well to atropine for 1–2 hours. Dopamine infusion was used to stabilize both heart rate and blood pressure. With supportive care, poisoned individuals become relatively asymptomatic within 24 hours of their ingestion. Patients may be discharged once asymptomatic, typically the day after ingestion, and do not have any known long term sequelae.

Conclusion

Zigadenus poisoning causes vomiting, hypotension and bradycardia. The hemodynamic instability may be treated with atropine administration and dopamine infusion.

Keywords: Zigadenus, death camas, bradycardia, hypotension, plant, emesis

Full Text

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Footnotes

Notes: There was no outside funding of any kind used for this study.

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