Skip to main content
Journal of Medical Toxicology logoLink to Journal of Medical Toxicology
. 2010 Apr 17;6(4):403–407. doi: 10.1007/s13181-010-0078-6

Compliance with Atypical Antipsychotic Triage Guidelines by Texas Poison Centers

Mathias B Forrester 1,
PMCID: PMC3550470  PMID: 20401557

Abstract

Triage guidelines for poison center management of atypical antipsychotic ingestions were published in December 2007. This investigation determined whether Texas poison centers already complied with a simplified version of these guidelines. All acute aripiprazole, clozapine, olanzapine, quetiapine, risperidone, and ziprasidone ingestions reported to Texas poison centers during 2000–2007 were identified. Exclusion criteria were the presence of coingestants, patient already at or en route to a health-care facility when the poison center was contacted, and chronic ingestion. Each case was evaluated whether it was managed in compliance with the simplified triage guidelines and the compliance rate calculated. For 2,611 total cases, the compliance rate was 64.1%. The rate was 71.7% for aripiprazole, 43.6% for clozapine, 71.6% for olanzapine, 60.8% for quetiapine, 65.5% for risperidone, and 59.0% for ziprasidone. The majority of acute atypical antipsychotic ingestions reported to Texas poison centers were managed according to a simplified version of recommended triage algorithm.

Keywords: Atypical antipsychotic, Management guidelines, Poison center

Full Text

The Full Text of this article is available as a PDF (91.4 KB).

Footnotes

Funding for this research was provided by a contract with the Commission on State Emergency Communications in Texas.

References

  • 1.Litovitz TL, Klein-Schwartz W, Rodgers GC, Cobaugh DJ, Youniss J, Omslaer JC, May ME, Woolf AD, Benson BE. 2001 annual report of the American Association of Poison Control Centers Toxic Exposure Surveillance System. Am J Emerg Med. 2002;20:391–452. doi: 10.1053/ajem.2002.34955. [DOI] [PubMed] [Google Scholar]
  • 2.Watson WA, Litovitz TL, Rodgers GC, Klein-Schwartz W, Youniss J, Rose SR, Borys D, May ME. 2002 annual report of the American Association of Poison Control Centers Toxic Exposure Surveillance System. Am J Emerg Med. 2003;21:353–421. doi: 10.1016/S0735-6757(03)00088-3. [DOI] [PubMed] [Google Scholar]
  • 3.Watson WA, Litovitz TL, Klein-Schwartz W, Rodgers GC, Youniss J, Reid N, Rouse WG, Rembert RS, Borys D. 2003 annual report of the American Association of Poison Control Centers Toxic Exposure Surveillance System. Am J Emerg Med. 2004;22:335–404. doi: 10.1016/j.ajem.2004.06.001. [DOI] [PubMed] [Google Scholar]
  • 4.Watson WA, Litovitz TL, Rodgers GC, Klein-Schwartz W, Reid N, Youniss J, Flanagan A, Wruk KM. 2004 Annual report of the American Association of Poison Control Centers Toxic Exposure Surveillance System. Am J Emerg Med. 2005;23:589–666. doi: 10.1016/j.ajem.2005.05.001. [DOI] [PubMed] [Google Scholar]
  • 5.Lai MW, Klein-Schwartz W, Rodgers GC, Abrams JY, Haber DA, Bronstein AC, Wruk KM. 2005 Annual Report of the American Association of Poison Control Centers' national poisoning and exposure database. Clin Toxicol (Phila) 2006;44:803–932. doi: 10.1080/15563650600907165. [DOI] [PubMed] [Google Scholar]
  • 6.Bronstein AC, Spyker DA, Cantilena LR, Green J, Rumack BH, Heard SE. 2006 annual report of the American Association of Poison Control Centers' National Poison Data System (NPDS) Clin Toxicol (Phila) 2007;45:815–917. doi: 10.1080/15563650701754763. [DOI] [PubMed] [Google Scholar]
  • 7.Bronstein AC, Spyker DA, Cantilena LR, Green JL, Rumack BH, Heard SE. 2007 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 25th Annual Report. Clin Toxicol (Phila) 2008;46:927–1057. doi: 10.1080/15563650802559632. [DOI] [PubMed] [Google Scholar]
  • 8.Cobaugh DJ, Erdman AR, Booze LL, Scharman EJ, Christianson G, Manoguerra AS, Caravati EM, Chyka PA, Woolf AD, Nelson LS, Troutman WG. Atypical antipsychotic medication poisoning: an evidence-based consensus guideline for out-of-hospital management. Clin Toxicol (Phila) 2007;45:918–942. doi: 10.1080/15563650701665142. [DOI] [PubMed] [Google Scholar]
  • 9.Forrester MB, Parra G. Compliance with selective serotonin reuptake inhibitor triage guidelines by Texas poison control centers. J Toxicol Environ Health A. 2008;71:304–309. doi: 10.1080/15287390701738483. [DOI] [PubMed] [Google Scholar]
  • 10.Nelson LS, Erdman AR, Booze LL, Cobaugh DJ, Chyka PA, Woolf AD, Scharman EJ, Wax PM, Manoguerra AS, Christianson G, Caravati EM, Troutman WG. Selective serotonin reuptake inhibitor poisoning: an evidence-based consensus guideline for out-of-hospital management. Clin Toxicol (Phila) 2007;45:315–332. doi: 10.1080/15563650701285289. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Medical Toxicology are provided here courtesy of Springer

RESOURCES