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. 1973 Jan;11(1):153–155. doi: 10.1128/jvi.11.1.153-155.1973

Selective Replication of Bacteriophage φ29 Deoxyribonucleic Acid in 6-(p-Hydroxyphenylazo)-Uracil-Treated Bacillus subtilis

Charles F Schachtele 1, Bernard E Reilly 1, Carol V De Sain 1, Melvin O Whittington 1, Dwight L Anderson 1
PMCID: PMC355073  PMID: 4630798

Abstract

Phage φ29 deoxyribonucleic acid (DNA) replicated under conditions where semiconservative DNA production in Bacillus subtilis host cells was blocked with 6-(p-hydroxyphenylazo)-uracil (HPUra). The time of initiation of φ29 DNA replication was not affected by HPUra, and normal quantities of viable phage were produced in the presence of the inhibitor. Studies with conditional lethal mutants of phage φ29 demonstrated the usefulness of HPUra for detection of viral-specific DNA production.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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