Enantioselective Synthesis of Biphenols from 1,4-Diketones by Traceless Central-to-Axial Chirality Exchange [Journal of the American Chemical Society 2011, 133, 18–20 DOI: 10.1021/ja108717r]. Fenghai Guo, Leah C. Konkol, and Regan J. Thomson.*
On page 18 the structure of compound 3 in Figure 1 was incorrectly drawn. The correct structure is shown below:
In the Supporting Information the following corrections should be made:
The optical rotation for compound 2a should be: [α]20D = −9.3 (c 0.06, CHCl3).
Data for compound 3a were inadvertently reported in the wrong enantiomeric series. The structures in the manuscript and experimental section are correct as drawn, but the data should be: Retention times: 23.8 min [minor enantiomer], 36.1 min [major enantiomer]. 99:1 enantiomeric ratio. [a]20D = +33.1 (c 0.08, EtOH).
Supporting Information Available: Detailed experimental procedures and spectral data for all compounds. This material is available free of charge via the Internet at http://pubs.acs.org/.