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. 1973 Jun;11(6):879–885. doi: 10.1128/jvi.11.6.879-885.1973

Prophage Induction by High Temperature in Thermosensitive dna Mutants Lysogenic for Bacteriophage Lambda

H Schuster 1, D Beyersmann 1, M Mikolajczyk 1, M Schlicht 1
PMCID: PMC355195  PMID: 4576518

Abstract

High-temperature treatment of thermosensitive dna mutants lysogenic for phage λ leads to prophage induction and release of phage (at the permissive temperature) in elongation-defective mutants of the genotypes dnaB, dnaE, and dnaG. In initiation-defective mutants no prophage induction occurs at 42 C in mutants of the genotype dnaA, whereas with a dnaC mutant as well as with strain HfrH 252 (map position not yet known) phages are released at 42 C. DNA degradation at the replication fork at 42 C is observed in all dnaB(λ) mutants tested, but not in mutants of the genotypes dnaE(λ) and dnaG(λ). Therefore, degradation of replication fork DNA is not a prerequisite for prophage induction.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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