Nonadherent bone marrow cells were derived from wild-type and TRAP-MVNP mice long bone. After 3 days of pretreatment of M-CSF, the cells were treated with RANKL and different doses of resveratrol (0, 10 μM, 25 μM, and 50 μM). After 3 days of further culture, cells were fixed and processed for TRAP staining. TRAP positive multinuclear cells (MNC) were counted under a microscope. *P < 0.05 as determined by two-way ANOVA with Bonferroni post-tests; ns, not significant.