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. 1973 Jun;11(6):1013–1016. doi: 10.1128/jvi.11.6.1013-1016.1973

Large-Molecular-Weight Precursors of Sindbis Virus Proteins

Milton J Schlesinger 1, Sondra Schlesinger 1
PMCID: PMC355211  PMID: 4736531

Abstract

Infection of chicken embryo fibroblasts with a temperature-sensitive mutant of Sindbis virus at the nonpermissive temperature leads to the accumulation of a large-molecular-weight protein. We have shown that this protein contains 14C-arginine tryptic peptides present in the three virion proteins. We have also found that a slightly smaller protein which is detected in Sindbis-infected BHK cells contains the 14C-arginine tryptic peptides of the two envelope proteins but not those of the capsid protein. Pulse-chase experiments indicate that the Sindbis virus protein in BHK cells is cleaved to the envelope proteins.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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