Skip to main content
Journal of Virology logoLink to Journal of Virology
. 1973 Jun;11(6):1017–1019. doi: 10.1128/jvi.11.6.1017-1019.1973

Specific Monovalent Cation Effects on Modification of Reovirus Infectivity by Chymotrypsin Digestion In Vitro

J Borsa 1, M D Sargent 1, T P Copps 1, D G Long 1, J D Chapman 1
PMCID: PMC355212  PMID: 4736532

Abstract

Specific monovalent cations control the modification of reovirus infectivity by chymotrypsin. Digestion in K+, Rb+, or Cs+ reduces infectivity several logs, whereas in Na+ or Li+ digestion markedly enhances infectivity.

Full text

PDF
1017

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Borsa J., Copps T. P., Sargent M. D., Long D. G., Chapman J. D. New intermediate subviral particles in the in vitro uncoating of reovirus virions by chymotrypsin. J Virol. 1973 Apr;11(4):552–564. doi: 10.1128/jvi.11.4.552-564.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Borsa J., Sargent M. D., Long D. G., Chapman J. D. Extraordinary effects of specific monovalent cations on activation of reovirus transcriptase by chymotrypsin in vitro. J Virol. 1973 Feb;11(2):207–217. doi: 10.1128/jvi.11.2.207-217.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Joklik W. K. Studies on the effect of chymotrypsin on reovirions. Virology. 1972 Sep;49(3):700–715. doi: 10.1016/0042-6822(72)90527-2. [DOI] [PubMed] [Google Scholar]
  4. SPENDLOVE R. S., SCHAFFER F. L. ENZYMATIC ENHANCEMENT OF INFECTIVITY OF REOVIRUS. J Bacteriol. 1965 Mar;89:597–602. doi: 10.1128/jb.89.3.597-602.1965. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Shatkin A. J., LaFiandra A. J. Transcription by infectious subviral particles of reovirus. J Virol. 1972 Oct;10(4):698–706. doi: 10.1128/jvi.10.4.698-706.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Spendlove R. S., McClain M. E., Lennette E. H. Enhancement of reovirus infectivity by extracellular removal or alteration of the virus capsid by proteolytic enzymes. J Gen Virol. 1970 Aug;8(2):83–94. doi: 10.1099/0022-1317-8-2-83. [DOI] [PubMed] [Google Scholar]
  7. Wallis C., Melnick J. L., Rapp F. Effects of pancreatin on the growth of reovirus. J Bacteriol. 1966 Jul;92(1):155–160. doi: 10.1128/jb.92.1.155-160.1966. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Journal of Virology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES