Fig. 3.
Dynamics of luciferase expression for representatives of human and animal papillomaviruses. Skin challenge was performed with luciferase-harbouring pseudovirions, corresponding to a total of 1×109 luciferase pseudogenome copies per inoculation. Readout was performed by in vivo imaging analysis daily for ten consecutive days. Control mice received phosphate-buffered saline instead of pseudovirions. The substrate luciferin was administered by intraperitoneal injection. Each experimental group consisted of five animals and results of the average radiance are given in mean p/s/cm2/sr ± standard deviation.