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Journal of Virology logoLink to Journal of Virology
. 1974 Jan;13(1):237–240. doi: 10.1128/jvi.13.1.237-240.1974

Oncogenicity of an Endogenous C-Type Virus Chemically Activated from Mouse Cells in Culture

John R Stephenson 1, Joel S Greenberger 1, Stuart A Aaronson 1
PMCID: PMC355282  PMID: 4129843

Abstract

RNA C-type viruses are known to exist in an unexpressed form in all mouse cells. These endogenous viruses can be activated from cells in tissue culture under certain experimental conditions. The biologic activity in vivo of one class of chemically-activated C-type virus has been studied. This virus is shown to induce a specific tumor, lymphatic leukemia, in mice of a low leukemic incidence strain.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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