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. 1974 Feb;13(2):548–550. doi: 10.1128/jvi.13.2.548-550.1974

Unfolding of the Host Genome After Infection of Escherichia coli with Bacteriophage T4

Daniel J Tutas 1, Jeanne M Wehner 1, James F Koerner 1
PMCID: PMC355330  PMID: 4589860

Abstract

The folded genome of Escherichia coli is converted to a slower-sedimenting form within 5 min after infection with bacteriophage T4 or T4nd28(den A)-amN82(44). Chloramphenicol sensitivity and response to UV-irradiation of the phage suggest participation of viral-induced functions.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. DELIHAS N. The ability of irradiated bacteriophage T2 to initiate the synthesis of deoxycytidylate hydroxymethylase in Escherichia coli. Virology. 1961 Feb;13:242–248. doi: 10.1016/0042-6822(61)90058-7. [DOI] [PubMed] [Google Scholar]
  2. Dirksen M. L., Wiberg J. S., Koerner J. F., Buchanan J. M. EFFECT OF ULTRAVIOLET IRRADIATION OF BACTERIOPHAGE T2 ON ENZYME SYNTHESIS IN HOST CELLS. Proc Natl Acad Sci U S A. 1960 Nov;46(11):1425–1430. doi: 10.1073/pnas.46.11.1425. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Hercules K., Munro J. L., Mendelsohn S., Wiberg J. S. Mutants in a nonessential gene of bacteriophage T4 which are defective in the degradation of Escherichia coli deoxyribonucleic acid. J Virol. 1971 Jan;7(1):95–105. doi: 10.1128/jvi.7.1.95-105.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Kutter E. M., Wiberg J. S. Degradation of cytosin-containing bacterial and bacteriophage DNA after infection of Escherichia coli B with bacteriophage T4D wild type and with mutants defective in genes 46, 47 and 56. J Mol Biol. 1968 Dec;38(3):395–411. doi: 10.1016/0022-2836(68)90394-x. [DOI] [PubMed] [Google Scholar]
  5. SEKIGUCHI M., COHEN S. S. THE SYNTHESIS OF MESSENGER RNA WITHOUT PROTEIN SYNTHESIS. II. SYNTHESIS OF PHAGE-INDUCED RNA AND SEQUENTIAL ENZYME PRODUCTION. J Mol Biol. 1964 May;8:638–659. doi: 10.1016/s0022-2836(64)80114-5. [DOI] [PubMed] [Google Scholar]
  6. Sadowski P. D., Hurwitz J. Enzymatic breakage of deoxyribonucleic acid. II. Purification and properties of endonuclease IV from T4 phage-infected Escherichia coli. J Biol Chem. 1969 Nov 25;244(22):6192–6198. [PubMed] [Google Scholar]
  7. Sadowski P. D., Warner H. R., Hercules K., Munro J. L., Mendelsohn S., Wiberg J. S. Mutants of bacteriophage T4 defective in the induction of T4 endonuclease II. J Biol Chem. 1971 May 25;246(10):3431–3433. [PubMed] [Google Scholar]
  8. Snustad D. P., Warner H. R., Parson K. A., Anderson D. L. Nuclear disruption after infection of Escherichia coli with a bacteriophage T4 mutant unable to induce endonuclease II. J Virol. 1972 Jul;10(1):124–133. doi: 10.1128/jvi.10.1.124-133.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Stonington O. G., Pettijohn D. E. The folded genome of Escherichia coli isolated in a protein-DNA-RNA complex. Proc Natl Acad Sci U S A. 1971 Jan;68(1):6–9. doi: 10.1073/pnas.68.1.6. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Warner H. R., Snustad P., Jorgensen S. E., Koerner J. F. Isolation of bacteriophage T4 mutants defective in the ability to degrade host deoxyribonucleic acid. J Virol. 1970 Jun;5(6):700–708. doi: 10.1128/jvi.5.6.700-708.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Worcel A., Burgi E. On the structure of the folded chromosome of Escherichia coli. J Mol Biol. 1972 Nov 14;71(2):127–147. doi: 10.1016/0022-2836(72)90342-7. [DOI] [PubMed] [Google Scholar]

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