FIG. 4.

Effects of pterosin A on serum insulin, HOMA-IR, and insulin intolerance in a dexamethasone-induced IR mouse model. Mice were intraperitoneally treated with dexamethasone (Dex, 1 mg/kg) for 1 week and then were orally treated with pterosin A (Pte, 100 mg/kg) or metformin (Met, 300 mg/kg) for 1 week, and serum insulin (A), HOMA-IR (B), and insulin tolerance test (C) were detected. Data are presented as mean ± SEM (n = 5). *P < 0.05 vs. control. #P < 0.05 vs. dexamethasone group without pterosin A.