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. 1974 Jul;14(1):110–115. doi: 10.1128/jvi.14.1.110-115.1974

Physical and Chemical Properties of an Oncornavirus Associated with a Murine Adrenal Carcinoma Cell Line

W Neal Burnette 1, Charles H Riggin 1, William M Mitchell 1
PMCID: PMC355483  PMID: 4134466

Abstract

A type C oncornavirus has been isolated from a continuous cell line of murine adrenal carcinoma in culture. The particles have a buoyant density of 1.165 g/cm3, exhibit typical type C morphology by electron microscopy, possess an RNA-dependent DNA polymerase, and have a high molecular weight RNA (6.1 × 106) which can be denatured to a homogeneous lower molecular weight species (3.2 × 106) when extracted from rapidly harvested “immature” virions. The virus is related antigenically to other mammalian oncornaviruses and exhibits a similar, although much more complex, sodium dodecyl sulfate gel electrophoretic profile of virion proteins when compared to the profiles of other type C RNA tumor viruses.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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