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. 1974 Aug;14(2):203–206. doi: 10.1128/jvi.14.2.203-206.1974

Prevention of Bacteriophage Adsorption to Staphylococcus aureus by Immunoglobulin G

Kristina Nordström 1, Arne Forsgren 1, Peter Cox 1
PMCID: PMC355504  PMID: 4277012

Abstract

Normal human and rabbit sera when incubated with Staphylococcus aureus inhibit the adsorption of bacteriophages. The bacteriophage adsorption was also inhibited by separated normal immunoglobulin M (IgM), F(ab′)2, and Fab-fragments of IgG. No inhibition was obtained with myeloma IgG or Fc-fragments of normal human and rabbit IgG. The results indicate that the serum inhibition of bacteriophage adsorption to S. aureus is not due to a binding of IgG to protein A on the surface of S. aureus.

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Selected References

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