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. 1974 Nov;14(5):1268–1273. doi: 10.1128/jvi.14.5.1268-1273.1974

Properties of Corynebacterium acnes Bacteriophage and Description of an Interference Phenomenon

Charles H Zierdt 1
PMCID: PMC355644  PMID: 4431080

Abstract

Nine virulent bacteriophages of the anaerobe Corynebacterium (Propionibacterium) acnes, the P-a series, are DNA phages, with long, curved nonretractile tails (130 nm) without tail plates or fibers. They have isometric heads (420 by 460 nm), and are placed in Bradley's group B-1. There is permanent plaque suppression at highest phage concentrations. After 100- to 1,000-fold dilution, plaques are evident. The latent period is 1 h and burst size 25. Cross-neutralization data of antisera for the nine phages are similar. There is an unexplained precipitous drop in plaque-forming units during the first 5 min of neutralization, after which the rate is linear for 2 h. They are sensitive to pH extremes but are partially protected even at pH 4 or 9 by storage at 4 C. They are resistant to ether and chloroform and are inactivated within 10 min at 70 C.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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