Skip to main content
NCBI home page
Journal of Virology logoLink to Journal of Virology
. 1974 Nov;14(5):1310–1313. doi: 10.1128/jvi.14.5.1310-1313.1974

Defective 30S Ribosomal Subunits After Infection of Escherichia coli by T2 Ghosts

Michel Simon 1, David Kennell 1
PMCID: PMC355651  PMID: 4610180

Abstract

Ribosomes from ghost-treated Escherichia coli can form in vitro initiation complexes but cannot translate added template RNA because of a defect in the 30S subunit; 16S rRNA is degraded.

Full text

PDF
1310

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BENZER S. Induced synthesis of enzymes in bacteria analyzed at the cellular level. Biochim Biophys Acta. 1953 Jul;11(3):383–395. doi: 10.1016/0006-3002(53)90057-2. [DOI] [PubMed] [Google Scholar]
  2. Bishop D. H., Claybrook J. R., Spiegelman S. Electrophoretic separation of viral nucleic acids on polyacrylamide gels. J Mol Biol. 1967 Jun 28;26(3):373–387. doi: 10.1016/0022-2836(67)90310-5. [DOI] [PubMed] [Google Scholar]
  3. Dubnoff J. S., Lockwood A. H., Maitra U. Studies on the role of guanosine triphosphate in polypeptide chain initiation in Escherichia coli. J Biol Chem. 1972 May 10;247(9):2884–2894. [PubMed] [Google Scholar]
  4. FRENCH R. C., SIMINOVITCH L. The action of T2 bacteriophage ghosts on Escherichia coli B. Can J Microbiol. 1955 Dec;1(9):757–774. doi: 10.1139/m55-090. [DOI] [PubMed] [Google Scholar]
  5. Fabricant R., Kennell D. Inhibition of host protein synthesis during infection of Escherichi coli by bacteriophage T4. 3. Inhibition by ghosts. J Virol. 1970 Dec;6(6):772–781. doi: 10.1128/jvi.6.6.772-781.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Fedorcsák I., Ehrenberg L. Effects of diethyl pyrocarbonate and methyl methanesulfonate on nucleic acids and nucleases. Acta Chem Scand. 1966;20(1):107–112. doi: 10.3891/acta.chem.scand.20-0107. [DOI] [PubMed] [Google Scholar]
  7. Godson G. N., Cox R. A. Structure of Escherichia coli ribosomes: effect of ribonuclease on the 30-S and 50-S subunits. Biochim Biophys Acta. 1970 Apr 15;204(2):489–501. doi: 10.1016/0005-2787(70)90169-3. [DOI] [PubMed] [Google Scholar]
  8. HERRIOTT R. M., BARLOW J. L. The protein coats or ghosts of coli phage T2. II. The biological functions. J Gen Physiol. 1957 Nov 20;41(2):307–331. doi: 10.1085/jgp.41.2.307. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Kennell D. Inhibition of host protein synthesis during infection of Escherichia coli by bacteriophage T4. I. Continued synthesis of host ribonucleic acid. J Virol. 1968 Nov;2(11):1262–1271. doi: 10.1128/jvi.2.11.1262-1271.1968. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Kennell D. Inhibition of host protein synthesis during infection of Escherichia coli by bacteriophage T4. II. Induction of host messenger ribonucleic acid and its exclusion from polysomes. J Virol. 1970 Aug;6(2):208–217. doi: 10.1128/jvi.6.2.208-217.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. LEVIN A. P., BURTON K. Inhibition of enzyme formation following infection of Escherichia coli with phage T2r. J Gen Microbiol. 1961 Jun;25:307–314. doi: 10.1099/00221287-25-2-307. [DOI] [PubMed] [Google Scholar]
  12. Nugent K., Kennell D. Polypeptide synthesis by extracts from Escherichia coli treated with T2 ghosts. J Virol. 1972 Dec;10(6):1199–1204. doi: 10.1128/jvi.10.6.1199-1204.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Revel M., Herzberg M., Becarevic A., Gros F. Role of protein factor in the functional binding of ribosomes to natural messenger RNA. J Mol Biol. 1968 Apr 14;33(1):231–249. doi: 10.1016/0022-2836(68)90291-x. [DOI] [PubMed] [Google Scholar]
  14. SHER I. H., MALLETTE M. F. The adaptive nature of the formation of lysine decarboxylase in Escherichia coli B. Arch Biochem Biophys. 1954 Oct;52(2):331–339. doi: 10.1016/0003-9861(54)90131-9. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Virology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES