Skip to main content
NCBI home page
Journal of Virology logoLink to Journal of Virology
. 1974 Dec;14(6):1411–1418. doi: 10.1128/jvi.14.6.1411-1418.1974

Complementation by Restricted Phage T1

J R Christensen 1
PMCID: PMC355669  PMID: 4610185

Abstract

The ability of restricted phage T1hr to complement stocks of T1am mutants carrying the P1 modification has been tested in mixed infection of Escherichia coli B(P1). Of the 18 genes tested, 15 could be complemented to give successful infection of approximately 10 to 25% of the cells, and 2 other genes consistently gave at least 5% complementation. The progeny phage produced in these infections was predominantly of the hr+am genotype. A mutant in gene 12 could be complemented very poorly, if at all. With one double mutant stock, the complementation obtained was nearly as good as the more poorly complemented of the two corresponding single mutants.

Full text

PDF
1411

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ARBER W., HATTMAN S., DUSSOIX D. ON THE HOST-CONTROLLED MODIFICATION OF BACTERIOPHAGE LAMBDA. Virology. 1963 Sep;21:30–35. doi: 10.1016/0042-6822(63)90300-3. [DOI] [PubMed] [Google Scholar]
  2. Arber W., Linn S. DNA modification and restriction. Annu Rev Biochem. 1969;38:467–500. doi: 10.1146/annurev.bi.38.070169.002343. [DOI] [PubMed] [Google Scholar]
  3. DREXLER H., CHRISTENSEN J. R. Genetic crosses between restricted and unrestricted phage T1 in lysogenic and non-lysogenic hosts. Virology. 1961 Jan;13:31–39. doi: 10.1016/0042-6822(61)90028-9. [DOI] [PubMed] [Google Scholar]
  4. FUKASAWA T. THE COURSE OF INFECTION WITH ABNORMAL BACTERIOPHAGE T4 CONTAINING NON-GLUCOSYLATED DNA ON ESCHERICHIA COLI STRAINS. J Mol Biol. 1964 Aug;9:525–536. doi: 10.1016/s0022-2836(64)80224-2. [DOI] [PubMed] [Google Scholar]
  5. Figurski D. H., Christensen J. R. Functional characterization of the genes of bacteriophage T1. Virology. 1974 Jun;59(2):397–407. doi: 10.1016/0042-6822(74)90453-x. [DOI] [PubMed] [Google Scholar]
  6. Freshman M., Wannag S. A., Christensen J. R. Cooperative infection of P1-lysogenic bacteria by restricted phage T1. Virology. 1968 Jul;35(3):427–438. doi: 10.1016/0042-6822(68)90221-3. [DOI] [PubMed] [Google Scholar]
  7. HATTMAN S. THE FUNCTIONING OF T-EVEN PHAGES WITH UNGLUCOSYLATED DNA IN RESTRICTING ESCHERICHIA COLI HOST CELLS. Virology. 1964 Nov;24:333–348. doi: 10.1016/0042-6822(64)90171-0. [DOI] [PubMed] [Google Scholar]
  8. Klein A. Mechanismen der wirtskontrollierten Modifikation des Phagen T1. Z Vererbungsl. 1965;96(4):346–363. [PubMed] [Google Scholar]
  9. Linn S., Lautenberger J. A., Eskin B., Lackey D. Host-controlled restriction and modification enzymes of Escherichia coli B. Fed Proc. 1974 May;33(5):1128–1134. [PubMed] [Google Scholar]
  10. Male C. J., Christensen J. R. Synthesis of messenger ribonucleic acid after bacteriophage T1 infection. J Virol. 1970 Dec;6(6):727–737. doi: 10.1128/jvi.6.6.727-737.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Michalke W. Erhöhte Rekombinationshäufigkeit an den Enden des T1-Chromosoms. Mol Gen Genet. 1967;99(1):12–33. doi: 10.1007/BF00306454. [DOI] [PubMed] [Google Scholar]
  12. Potts T. V., Christensen J. R. Physiological study of cooperative infection by restricted bacteriophage T1. J Virol. 1974 Dec;14(6):1319–1325. doi: 10.1128/jvi.14.6.1319-1325.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Skaar P. D., Garen A. THE ORIENTATION AND EXTENT OF GENE TRANSFER IN ESCHERICHIA COLI. Proc Natl Acad Sci U S A. 1956 Sep;42(9):619–624. doi: 10.1073/pnas.42.9.619. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Terzi M. Physiology of bacteriophage lambda in the restrictive host. J Mol Biol. 1968 May 28;34(1):165–173. doi: 10.1016/0022-2836(68)90242-8. [DOI] [PubMed] [Google Scholar]
  15. UETAKE H., TOYAMA S., HAGIWARA S. ON THE MECHANISM OF HOST-INDUCED MODIFICATION. MULTIPLICITY ACTIVATION AND THERMOLABILE FACTOR RESPONSIBLE FOR PHAGE GROWTH RESTRICTION. Virology. 1964 Feb;22:202–213. doi: 10.1016/0042-6822(64)90005-4. [DOI] [PubMed] [Google Scholar]
  16. Winstead L., Drexler H. Nature of Escherichia coli B(P1) yielder cells at the time of infection with restricted T1. J Virol. 1969 Jun;3(6):566–569. doi: 10.1128/jvi.3.6.566-569.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Journal of Virology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES