Abstract
Specific transduction of inducible (eroA) and constitutive (eroB) erythromycin resistance is mediated by thymineless induced lysates from derivatives of Staphylococcus aureus strain 8325(N)thy. Both loci can coexist in the same cell but segregate by transduction or transformation. The gene(s) is probably integrated in the recipient chromosome and excised at thymine starvation.
Full text
PDF







Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- ARBER W. Transduction of chromosomal genes and episomes in Escherichia coli. Virology. 1960 May;11:273–288. doi: 10.1016/0042-6822(60)90066-0. [DOI] [PubMed] [Google Scholar]
- Bronson D. L., Pattee P. A. Genetic analysis of resistance to erythromycin and oleandomycin in Staphylococcus aureus. Can J Microbiol. 1972 Apr;18(4):429–434. doi: 10.1139/m72-067. [DOI] [PubMed] [Google Scholar]
- Clewell D. B., Helinski D. R. Supercoiled circular DNA-protein complex in Escherichia coli: purification and induced conversion to an opern circular DNA form. Proc Natl Acad Sci U S A. 1969 Apr;62(4):1159–1166. doi: 10.1073/pnas.62.4.1159. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Dornbusch K., Dahlström A. A genetic study of inducible erythromycin resistance in Staphylococcus aureus. Acta Pathol Microbiol Scand B Microbiol Immunol. 1973 Oct;81(5):497–507. doi: 10.1111/j.1699-0463.1973.tb02235.x. [DOI] [PubMed] [Google Scholar]
- GARROD L. P. The erythromycin group of antibiotics. Br Med J. 1957 Jul 13;2(5036):57–63. doi: 10.1136/bmj.2.5036.57. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hashimoto H., Oshima H., Mitsuhashi S. Drug resistance of staphylococci. IX. Inducible resistance to macrolide antibiotics in Staphylococcus aureus. Jpn J Microbiol. 1968 Sep;12(3):321–327. [PubMed] [Google Scholar]
- Kono M., Hashimoto H., Mitsuhashi S. Drug resistance to staphylococci. 3. Resistance to some macrolide antibiotics and inducible system. Jpn J Microbiol. 1966 Apr;10(1):59–66. [PubMed] [Google Scholar]
- Lai C. J., Weisblum B., Fahnestock S. R., Nomura M. Alteration of 23 S ribosomal RNA and erythromycin-induced resistance to lincomycin and spiramycin in Staphylococcus aureus. J Mol Biol. 1973 Feb 15;74(1):67–72. doi: 10.1016/0022-2836(73)90355-0. [DOI] [PubMed] [Google Scholar]
- Lindberg M., Novick R. P. Plasmid-specific transformation in Staphylococcus aureus. J Bacteriol. 1973 Jul;115(1):139–145. doi: 10.1128/jb.115.1.139-145.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lindberg M., Sjöström J. E., Johansson T. Transformation of chromosomal and plasmid characters in Staphylococcus aureus. J Bacteriol. 1972 Feb;109(2):844–847. doi: 10.1128/jb.109.2.844-847.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
- MITSUHASHI S., HASHIMOTO H., KONO M., MORIMURA M. DRUG RESISTANCE OF STAPHYLOCOCCI. II. JOINT ELIMINATION AND JOINT TRANSDUCTION OF THE DETERMINANTS OF PENICILLINASE PRODUCTION AND RESISTANCE TO MACROLIDE ANTIBIOTICS. J Bacteriol. 1965 Apr;89:988–992. doi: 10.1128/jb.89.4.988-992.1965. [DOI] [PMC free article] [PubMed] [Google Scholar]
- NOVICK R. P. ANALYSIS BY TRANSDUCTION OF MUTATIONS AFFECTING PENICILLINASE FORMATION IN STAPHYLOCOCCUS AUREUS. J Gen Microbiol. 1963 Oct;33:121–136. doi: 10.1099/00221287-33-1-121. [DOI] [PubMed] [Google Scholar]
- Novick R. P., Bouanchaud D. The problems of drug-resistant pathogenic bacteria. Extrachromosomal nature of drug resistance in Staphylococcus aureus. Ann N Y Acad Sci. 1971 Jun 11;182:279–294. doi: 10.1111/j.1749-6632.1971.tb30664.x. [DOI] [PubMed] [Google Scholar]
- Novick R. P. Penicillinase plasmids of Staphylococcus aureus. Fed Proc. 1967 Jan-Feb;26(1):29–38. [PubMed] [Google Scholar]
- Novick R. P., Roth C. Plasmid-linked resistance to inorganic salts in Staphylococcus aureus. J Bacteriol. 1968 Apr;95(4):1335–1342. doi: 10.1128/jb.95.4.1335-1342.1968. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Novick R. Properties of a cryptic high-frequency transducing phage in Staphylococcus aureus. Virology. 1967 Sep;33(1):155–166. doi: 10.1016/0042-6822(67)90105-5. [DOI] [PubMed] [Google Scholar]
- Richmond M. H., Johnston J. The reversible transition of certain genes in Staphylococcus aureus between the integrated and the extra-chromosomal state. Genet Res. 1969 Jun;13(3):267–274. doi: 10.1017/s0016672300002950. [DOI] [PubMed] [Google Scholar]
- Rudin L., Lindberg M. Thymineless bacteriophage induction in Staphylococcus aureus. I. High-frequency transduction with lysates containing a bacteriophage related to bacteriophage phi 11. J Virol. 1975 Dec;16(6):1357–1366. doi: 10.1128/jvi.16.6.1357-1366.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Rudin L., Sjöström J. E., Lindberg M., Philipson L. Factors affecting competence for transformation in Staphylococcus aureus. J Bacteriol. 1974 Apr;118(1):155–164. doi: 10.1128/jb.118.1.155-164.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Rush M. G., Gordon C. N., Novick R. P., Warner R. C. Penicillinase plasmid DNA from Staphylococcus aureus. Proc Natl Acad Sci U S A. 1969 Aug;63(4):1304–1310. doi: 10.1073/pnas.63.4.1304. [DOI] [PMC free article] [PubMed] [Google Scholar]
- WEAVER J. R., PATTEE P. A. INDUCIBLE RESISTANCE TO ERYTHROMYCIN IN STAPHYLOCOCCUS AUREUS. J Bacteriol. 1964 Sep;88:574–580. doi: 10.1128/jb.88.3.574-580.1964. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Weisblum B., Siddhikol C., Lai C. J., Demohn V. Erythromycin-inducible resistance in Staphylococcus aureus: requirements for induction. J Bacteriol. 1971 Jun;106(3):835–847. doi: 10.1128/jb.106.3.835-847.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wyman L., Goering R. V., Novick R. P. Genetic control of chromosomal and plasmid recombination in Staphylococcus aureus. Genetics. 1974 Apr;76(4):681–702. doi: 10.1093/genetics/76.4.681. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Zouzias D., Rush M., Murphy E., Novick R. Studies on plasmid replication. II. In vivo transcription and its control in penicillinase plasmids from Staphylococcus aureus. J Mol Biol. 1973 Sep 25;79(3):471–480. doi: 10.1016/0022-2836(73)90399-9. [DOI] [PubMed] [Google Scholar]
