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. 1975 Dec;16(6):1375–1379. doi: 10.1128/jvi.16.6.1375-1379.1975

Alkali lability of bacteriophage phi W-14 DNA.

H A Lewis, R C Miller Jr, J C Stone, R A Warren
PMCID: PMC355745  PMID: 1202241

Abstract

The molecular weight of bacteriophage phi W-14 DNA, determined by velocity sedimentation in neutral sucrose gradients, was 92 +/- 6 X 10(6). The DNA showed marked fragmentation in alkaline sucrose gradients. This fragmentation was not a consequence of preexisting single-strand interruptions in the DNA, since thermal denaturation of DNA yielded intact single strands. The alpha-putrescinylthymine groups in phi W-14 DNA appeared to be labile; some, or parts of some, of these groups were cleaved from the DNA in alkali.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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