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. 1971 May;7(5):539–548. doi: 10.1128/jvi.7.5.539-548.1971

Deoxyribonucleic Acid Polymerase of Rous Sarcoma Virus: Studies on the Mechanism of Double-Stranded Deoxyribonucleic Acid Synthesis

Anthony Faras a, Lois Fanshier a, Axel-Claude Garapin a,1, Warren Levinson a, J Michael Bishop a
PMCID: PMC356161  PMID: 4326751

Abstract

The deoxyribonucleic acid (DNA) polymerase of Rous sarcoma virus synthesizes both single- and double-stranded DNA, utilizing the ribonucleic acid (RNA) of the viral genome as the initial template. Results of pulse-chase experiments indicate that the single-stranded DNA serves as unconserved template and precursor for the synthesis of double-stranded DNA. The latter reaction is apparently initiated in association with the viral RNA and may involve a partially double-stranded intermediate form.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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