Table 2.
Validation by BioGRID, breaking down according to experimental systemsa
| BioGRID physical interactions |
||||||
|---|---|---|---|---|---|---|
| Edge group | Number of edges | All | AP | Y2H | PCA | Other |
| BioGRID | 73 929 | 73 929 (1.00) | 52 842 (0.71) | 9303 (0.12) | 5237 (0.07) | 13 080 (0.18) |
| Krogan | ||||||
| Predicted | 2870 | 1033 (0.36) | 983 (0.34) | 134 (0.05) | 35 (0.01) | 180 (0.06) |
| Removed | 2870 | 412 (0.14) | 393 (0.14) | 48 (0.02) | 16 (0.01) | 67 (0.02) |
| Confirmed | 4253 | 2732 (0.64) | 2682 (0.63) | 595 (0.14) | 165 (0.04) | 770 (0.18) |
| Random | 7123 | 54 (0.01) | 33 (0.00) | 13 (0.00) | 1 (0.00) | 13 (0.00) |
| Yu | ||||||
| Predicted | 706 | 65 (0.09) | 52 (0.07) | 35 (0.05) | 4 (0.01) | 20 (0.03) |
| Removed | 706 | 114 (0.16) | 53 (0.07) | 85 (0.12) | 3 (0.00) | 19 (0.03) |
| Confirmed | 935 | 405 (0.43) | 304 (0.33) | 290 (0.31) | 35 (0.04) | 169 (0.18) |
| Random | 1641 | 7 (0.00) | 3 (0.00) | 1 (0.00) | 0 (0.00) | 3 (0.00) |
| Tarassov | ||||||
| Predicted | 1203 | 135 (0.11) | 96 (0.08) | 39 (0.03) | 23 (0.02) | 42 (0.03) |
| Removed | 1203 | 109 (0.09) | 81 (0.07) | 22 (0.02) | 15 (0.01) | 26 (0.02) |
| Confirmed | 1333 | 352 (0.26) | 301 (0.23) | 143 (0.11) | 34 (0.03) | 121 (0.09) |
| Random | 2536 | 24 (0.01) | 18 (0.01) | 2 (0.00) | 1 (0.00) | 6 (0.00) |
aValues in parentheses are fractions of edges validated.