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. 1972 Jul;10(1):99–114. doi: 10.1128/jvi.10.1.99-114.1972

Direction of Translation and Size of Bacteriophage φX174 Cistrons

Robert M Benbow 1, Robert F Mayol 1, Joanna C Picchi 1, Robert L Sinsheimer 1
PMCID: PMC356431  PMID: 16789133

Abstract

Translation of the bacteriophage φX174 genome follows cistron order D-E-F-G-H-A-B-C. To establish this, the position of a nonsense mutation on the genetic map was compared with the physical size (molecular weight) of the appropriate protein fragment generated in nonpermissive cells. Distances on the φX174 genetic map and distances on a physical map constructed from the molecular weights of φX174 proteins and protein fragments are proportional over most of the genome with the exception of the high recombination region within cistron A.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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