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. 1972 Jul;10(1):153–156. doi: 10.1128/jvi.10.1.153-156.1972

Rescue of Rous Sarcoma Virus from Rous Sarcoma Virus-Transformed Mammalian Cells 1

John M Coffin a,2
PMCID: PMC356438  PMID: 4339192

Abstract

Rat cells transformed by the B77 strain of avian sarcoma virus produce no virus-like particles, yet B77 virus was rescued from these cells by Sendai virus-mediated fusion with chicken cells. This virus rescue was not affected by treatment of the chicken cells with agents that rendered the cells incapable of dividing, although such treatment greatly reduced the ability of the chicken cells to plate as infectious centers after infection with B77 virus. Fusion of R(B77) cells with chicken erythrocytes also led to virus rescue, although with less efficiency than fusion with chicken fibroblasts. Therefore, virus rescue was probably due to a factor or factors contributed by chicken cells which aid in virus production.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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