Abstract
Functional gene 2 product was found to be necessary for fd deoxyribonucleic acid (DNA) synthesis throughout the life cycle of the virus. Bacteria which had been infected with a temperature-sensitive gene 2 mutant ceased to make virus-specific DNA when transferred to restrictive conditions at any time after infection, although current rounds of replication were completed.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Alberts B., Frey L., Delius H. Isolation and characterization of gene 5 protein of filamentous bacterial viruses. J Mol Biol. 1972 Jul 14;68(1):139–152. doi: 10.1016/0022-2836(72)90269-0. [DOI] [PubMed] [Google Scholar]
- Beacham I. R., Barth P. T., Pritchard R. H. Constitutivity of thymidine phosphorylase in deoxyriboaldolase negative strains: dependence on thymine requirement and concentration. Biochim Biophys Acta. 1968 Sep 24;166(2):589–592. doi: 10.1016/0005-2787(68)90251-7. [DOI] [PubMed] [Google Scholar]
- Brutlag D., Schekman R., Kornberg A. A possible role for RNA polymerase in the initiation of M13 DNA synthesis. Proc Natl Acad Sci U S A. 1971 Nov;68(11):2826–2829. doi: 10.1073/pnas.68.11.2826. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Denhardt D. T. A membrane-filter technique for the detection of complementary DNA. Biochem Biophys Res Commun. 1966 Jun 13;23(5):641–646. doi: 10.1016/0006-291x(66)90447-5. [DOI] [PubMed] [Google Scholar]
- Denhardt D. T., Dressler D. H., Hathaway A. THE ABORTIVE REPLICATION OF PhiX174 DNA IN A RECOMBINATION-DEFICIENT MUTANT OF Escherichia coli. Proc Natl Acad Sci U S A. 1967 Mar;57(3):813–820. doi: 10.1073/pnas.57.3.813. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Francke B., Ray D. S. Fate of parental phi X174-DNA upon infection of starved thymine-requiring host cells. Virology. 1971 Apr;44(1):168–187. doi: 10.1016/0042-6822(71)90163-2. [DOI] [PubMed] [Google Scholar]
- Francke B., Ray D. S. Formation of the parental replicative form DNA of bacteriophage phi-X174 and initial events in its replication. J Mol Biol. 1971 Nov 14;61(3):565–586. doi: 10.1016/0022-2836(71)90065-9. [DOI] [PubMed] [Google Scholar]
- Garen A., Garen S., Wilhelm R. C. Suppressor genes for nonsense mutations. I. The Su-1, Su-2 and Su-3 genes of Escherichia coli. J Mol Biol. 1965 Nov;14(1):167–178. doi: 10.1016/s0022-2836(65)80238-8. [DOI] [PubMed] [Google Scholar]
- Henry T. J., Pratt D. The proteins of bacteriophage M13. Proc Natl Acad Sci U S A. 1969 Mar;62(3):800–807. doi: 10.1073/pnas.62.3.800. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hohn B., Lechner H., Marvin D. A. Filamentous bacterial viruses. I. DNA synthesis during the early stages of infection with fd. J Mol Biol. 1971 Feb 28;56(1):143–154. doi: 10.1016/0022-2836(71)90090-8. [DOI] [PubMed] [Google Scholar]
- Lindqvist B. H., Sinsheimer R. L. The process of infection with bacteriophage phi-X174. XV. Bacteriophage DNA synthesis in abortive infections with a set of conditional lethal mutants. J Mol Biol. 1967 Nov 28;30(1):69–80. doi: 10.1016/0022-2836(67)90244-6. [DOI] [PubMed] [Google Scholar]
- Marvin D. A., Hohn B. Filamentous bacterial viruses. Bacteriol Rev. 1969 Jun;33(2):172–209. doi: 10.1128/br.33.2.172-209.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Marvin D. A., Schaller H. The topology of DNA from the small filamentous bacteriophage fd. J Mol Biol. 1966 Jan;15(1):1–7. doi: 10.1016/s0022-2836(66)80204-8. [DOI] [PubMed] [Google Scholar]
- Oey J. L., Knippers R. Properties of the isolated gene 5 protein of bacteriophage fd. J Mol Biol. 1972 Jul 14;68(1):125–138. doi: 10.1016/0022-2836(72)90268-9. [DOI] [PubMed] [Google Scholar]
- Pratt D., Erdahl W. S. Genetic control of bacteriophage M13 DNA synthesis. J Mol Biol. 1968 Oct 14;37(1):181–200. doi: 10.1016/0022-2836(68)90082-x. [DOI] [PubMed] [Google Scholar]
- Pratt D., Tzagoloff H., Erdahl W. S. Conditional lethal mutants of the small filamentous coliphage M13. I. Isolation, complementation, cell killing, time of cistron action. Virology. 1966 Nov;30(3):397–410. doi: 10.1016/0042-6822(66)90118-8. [DOI] [PubMed] [Google Scholar]
- Ray D. S. Replication of bacteriophage M13. II. The role of replicative forms in single-strand synthesis. J Mol Biol. 1969 Aug 14;43(3):631–643. doi: 10.1016/0022-2836(69)90364-7. [DOI] [PubMed] [Google Scholar]
- Ray D. S. Replication of bacteriophage M13. IV. Synthesis of M13-specific DNA in the presence of chloramphenicol. J Mol Biol. 1970 Oct 28;53(2):239–250. doi: 10.1016/0022-2836(70)90297-4. [DOI] [PubMed] [Google Scholar]
- Rush M. G., Warner R. C. Alkali denaturation of covalently closed circular duplex deoxyribonucleic acid. J Biol Chem. 1970 May 25;245(10):2704–2708. [PubMed] [Google Scholar]
- STACEY K. A., SIMSON E. IMPROVED METHOD FOR THE ISOLATION OF THYMINE-REQUIRING MUTANTS OF ESCHERICHIA COLI. J Bacteriol. 1965 Aug;90:554–555. doi: 10.1128/jb.90.2.554-555.1965. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sinsheimer R. L. Bacteriophage phi-X174 and related viruses. Prog Nucleic Acid Res Mol Biol. 1968;8:115–169. [PubMed] [Google Scholar]
- Smilowitz H., Lodish H., Robbins P. W. Synthesis of the major bacteriophage fl coat protein. J Virol. 1971 Jun;7(6):776–782. doi: 10.1128/jvi.7.6.776-782.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Smith J. D., Barnett L., Brenner S., Russell R. L. More mutant tyrosine transfer ribonucleic acids. J Mol Biol. 1970 Nov 28;54(1):1–14. doi: 10.1016/0022-2836(70)90442-0. [DOI] [PubMed] [Google Scholar]
- Studier F. W. Conformational changes of single-stranded DNA. J Mol Biol. 1969 Apr;41(2):189–197. doi: 10.1016/0022-2836(69)90384-2. [DOI] [PubMed] [Google Scholar]
- Tseng B. Y., Marvin D. A. Filamentous bacterial viruses. V. Asymmetric replication of fd duplex deoxyribonucleic acid. J Virol. 1972 Sep;10(3):371–383. doi: 10.1128/jvi.10.3.371-383.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Vinograd J., Lebowitz J., Radloff R., Watson R., Laipis P. The twisted circular form of polyoma viral DNA. Proc Natl Acad Sci U S A. 1965 May;53(5):1104–1111. doi: 10.1073/pnas.53.5.1104. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Warmaar S. O., Cohen J. A. A quantitative assay for DNA-DNA hybrids using membrane filters. Biochem Biophys Res Commun. 1966 Aug 23;24(4):554–558. doi: 10.1016/0006-291x(66)90356-1. [DOI] [PubMed] [Google Scholar]