. Author manuscript; available in PMC: 2014 Jan 22.

Published in final edited form as: Biochemistry. 2013 Jan 10;52(3):447–455. doi: 10.1021/bi301066z

Table 1.

Haem iron ligand on- and off-rates and equilibrium constants at each site

Haem Protein	location	k_{o2 on} (mM⁻¹s⁻¹)	k_{o2 off} (s⁻¹)	K_{d O2_pen} (μM)	K_{dO2_actual} (μM)	k_{his on} (s⁻¹)	k_{his off} (s⁻¹)	K_A,his
HP7H7F	Loop end	1200 ± 200^c	4.8 ± 0.4^c	3.9 ± 0.9^c	120 ± 50^c	160 ± 20^b	5.6 ± 0.3^b	29 ± 5^b
HP7	Open end	1500 ± 100^c	1.3 ± 0.2^c	0.9 ± 0.2^c	17 ± 4^c	310^a	17^a	18^a

Data from reference 3

Data from reference 6

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