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. 1973 Sep;12(3):588–593. doi: 10.1128/jvi.12.3.588-593.1973

Sedimentation Changes of L Cells in a Density Gradient Early After Infection with Vaccinia Virus

Frederick R Ball 1, Edward L Medzon 1
PMCID: PMC356666  PMID: 4795833

Abstract

By 2 h postinfection, LM cells infected with vaccinia virus show a shift in their distribution when separated on a Ficoll density gradient. This shift is dependent on both time and the multiplicity of infection and is due, at least in part, to an increase in cell size. Those cells which do shift in position in the gradient represent infected members of the population. Physical changes induced in virus-infected cells can be utilized for studying early events in virus replication.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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