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. 1973 Nov;12(5):1028–1030. doi: 10.1128/jvi.12.5.1028-1030.1973

Comparison of the Lipids of Intracellular and Extracellular Rabies Viruses

Harvey R Schlesinger 1, Henry J Wells 1, Klaus Hummeler 1
PMCID: PMC356732  PMID: 4797265

Abstract

The lipid composition of both intracellular and extracellular forms of the ERA strain of rabies virus grown in BHK/21 cells was determined. The lipids from purified preparations of both intracellular and extracellular virus yielded 57 and 58% neutral lipid, respectively. The phospholipids of the intracellular and extracellular virus constituted 43 and 42%, respectively. Triglyceride and cholesterol appear to be the major neutral lipids, whereas sphingomyelin, phosphatidylethanolamine, and phosphatidylcholine comprise the major bulk of phospholipid in both virus types. The molar ratio of cholesterol to phospholipid was 0.87 (intracellular) and 0.92 (extracellular). On the basis of the data presented, it is reasonable to assume that the lipids of both intracellular and extracellular rabies virus are similar.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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