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. 1973 Dec;12(6):1272–1278. doi: 10.1128/jvi.12.6.1272-1278.1973

Restricted Replication of Vesicular Stomatitis Virus in Human Lymphoblastoid Cells

Maja Nowakowski 1, Barry R Bloom 1, Ellie Ehrenfeld 1, Donald F Summers 1
PMCID: PMC356768  PMID: 4357508

Abstract

Replication of vesicular stomatitis virus (VSV) is restricted in one human lymphoblastoid cell line (Raji), but not in another similar cell line (Wil-2), compared with growth in HeLa cells. This restriction is characterized by a low proportion of cells yielding infectious virus and is associated with limited production of 42S virion RNA. Primary transcription of 13S and 26S VSV-specific RNA is not restricted in Raji cells, and the 13S RNA produced contains adenylate-rich sequences. This suggests that the block in Raji cells involves some step required for the replication of virion RNA.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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